Form the middle age of the Ming Dynasty, Chinese literature had been showing the tendency of modemization. Li Zhi and the three Yuan brothers had important status in this evolution. This writing not only describes the relations between Li Zhi and the three Yuan brothers, the effects of Li Zhi on the three Yuan brothers both at the living attitude and at the viewpoints of literature, the differences between them, but also studies their status and influence in the Chinese Cultural Enlightenment at that time.