The contemporary science and technology is more and more multidisciplinary intersecting and mutual penetrating,and cultivating the interdisciplinary talents, is an important foundation of the different disciplines, and the development of new disciplines. However, the right analysis of the quality demand of the interdisciplinary graduates is important to the cultivation of interdisciplinary talents. This paper studies the quality demand of interdisciplinary graduates in 3 aspects, and put forward an evaluation model of the quality demand of the interdisciplinary graduates. This has a good reference for a reasonable cultivation mechanism of the graduates.