The ground-breaking advancing of artificial intelligence has echoed the prophecy of Kevin Kelly that machine will go“out of control” of humans in its autonomous development,incurring humans' fear to be enslaved or destroyed by the machine.Based on Derrida's deconstruction,the wisdom of“no mind about control” mentioned by Kevin Kelly,and human-machine cooperation or symbiosis and coevolution proposed by other scholars,through the analysis of how the out-of-control development of the machine decomposes the traditional human-machine binary opposition and the definition of the subject,the paper aims to point out that against the backdrop of the posthuman era in which the boundary between the real and the simulacrum is effaced and the definition of“human” is constantly being refreshed,the traditional binary oppositional view of human and machine is out of mode and will bring about new relationship crises.Concerning this,humans need to get out of the mentality to regard the machine as the object and the other,turn to embrace the variant and dynamic postmodern subjects,as well as to transit from the centered control by the single subject—the humans—to a partnership relationship between human and machine featured by coevolution and co-control.Only in this way can a harmonious human-machine interaction be maintained,thus in the end melting the humans' fear towards the out-of-control development of the machine.