After the founding of new China, with the idea of “learning from the Soviet Union”, the departments in the higher education of China were adjusted in the national scope before and after 1952.One of the key departments adjustment is concentrated on the establishment of a large number of single industrial colleges with Beijing Institute of Iron and Steel as the representative.The review of the discipline construction and important results of Beijing Institute of Iron and Steel from 1952 to 1966, and the summing up of the characteristics, dynamic mechanism and experience in the discipline construction, have a important reference to understand the situations of the similar colleges and universities over the same period in China, and also, have inspiration and reference to the discipline construction in the new period.