Abstract: In the face of the reality of the acceleration of the evolution of the world’s great changes unseen in a century, it is necessary to enhance the sense of distress, prepare for danger in times of peace and effectively respond to external risks and challenges by comprehensively promoting the construction of a strong country and the great cause of national rejuvenation with Chinese-style modernization.The Communist Party of China’s sense of distress embodies the responsibility of the Party’s members to worry about the Party, the country and the people. The Communist Party of China’s sense of distress contains rich philosophical thinking. From the perspective of dialectical materialism and historical materialism, the Communist Party of China’s sense of distress internally realizes the organic unity of epistemology, practice, history and methodology. Exploring the philosophical foundation of the Communist Party of China’s sense of distress is of great theoretical and practical significance for further exerting its scientific efficiency and promoting the Party’s self-revolution and social revolution.