Abstract: Deepening and merging the construction of collaborative supervision of “Discipline inspection commission, Political inspection, Accounting supervision and Audit” (DPAA), is an important way to enhance the modernization of the governance system and governance capacity for colleges and universities. It is also an effective starting point to better transform the advantages of the system into governance efficacy. This study is conducted based on the necessity and value of the times of collaborative supervision in constructing the DPAA, the basic theory of Synergistic learning, and the current situation and difficulties of DPAA collaborative supervision in colleges and universities. Also, the study provides and analyzes a specific scheme and path from fours aspects: (1) discovering and solving problems as a common goal of all supervisory work, (2) joint planning, unified supervision standards, and promotion of achievement sharing; (3) fully utilizing big data and information technology, and (4) strengthening the personnel team and cultivating a collaborative supervision culture. Thus, a comprehensive mechanism has been explored for the formation of a long-term coordinated and effective supervision force, which provides a practical and operational path for building the “four beams and eight pillars” of the supervision system in colleges and universities.