Abstract: On April 21, 2022, General Secretary Xi Jinping wrote back to the senior professors of University of Science and Technology Beijing (USTB), affirming the positive contributions USTB has made over the past 70 years since its founding, and putting forward new requirements and hopes for the development of USTB, providing fundamental guidance for the development of USTB’s undertakings. At present and for a period in the future, it is the primary political task of the school to earnestly study, publicize and implement the important spirit of Xi Jinping’s reply, and effectively promote the effective implementation of the spirit of the reply.