Abstract: Attaching importance to youth work has always been the fine tradition of the Communist Party of China. This year is the centenary since the founding of the Communist Youth League. Reviewing the logic and experience of the Communist Youth League’s youth work over the century will be of great benefit to the Communist Youth League’s youth work in the new era. From the theoretical basis, the leaders of the Communist Party of China in successive generations carry out the youth work of the Communist Youth League under the guidance of Marxism, which provide a rich theoretical source for the youth work of the Communist Youth League. From a historical perspective, the youth work of the Communist Youth League has experienced four stages to initiate youth to participate in the revolution, to encourage them to work hard, to excite them to innovate and make progress, and to educate them to build a successful career. From the perspective of practice characteristics, Youth League work of the Communist Youth League always adheres to the combination of political and mass nature, keeping pace with the times and adjusting measures to local conditions, and adheres to the combination of theory and practice. From the perspective of experience and enlightenment, the youth work of the Communist Youth League should serve the overall situation of the center and grasp the direction of progress, adhere to the party’s leadership and grasp the political orientation, attach importance to group construction and give full play to unique advantages, pay attention to practice and improve working methods, and change work style and strengthen weak links.