Abstract: In the process of collision and integration of science and the national culture, especially as China has a long history, the cultural essence of science is more easily have an unexpected appearance. Therefore, dissemination of western learning to the east is a characteristic field to understanding science. The introduction of western science has three levels of influence on Chinese culture. Firstly is the influence on Chinese traditional science; secondly is the influence to the Confucianism, Taoism and other cultural forms; thirdly is the influence on the entire Chinese culture. Around these three levels, the author makes a useful discussion.