Abstract: From the perspective of organizational sociology, this article discusses the organizational principles and implementation strategies of economic law macro-control in the context of epidemic prevention and control. The macro-control of economic law follows the control paradigm of “plan-economic policy-adjustment means”, which embodies a typical organizational operation process. In the context of epidemic prevention and control, the fiscal policy, monetary policy, and resumption of production and work policies implemented by the economic law macro-control interact with the administrative system environment and market technology environment, thereby gaining the “legitimacy” recognition of the institutional environment. Administrative organizations and enterprise organizations constitute the organizational basis for macro-control of economic law. In response to the characteristics of epidemic prevention and control, economic law macro-control should implement overall control led by administrative organizations, actively respond to the production and operation difficulties faced by enterprise organizations, and follow the principle of proportionality in organizational operations.