Abstract: Since 1949，Lenin's Materialism and Empiriocriticism has become China's official philosophy.The view of “physics crisis and revolution” was discussed from “two classes，two kinds of world outlook and two philosophy route” ，and this view became the theoretical basis for China to criticize the theory of natural science and transform scientists for a long time.It was proved in recent thirty years that Criticism of Materialism and Experience as the guiding in the philosophy of natural science is problematic in China.Mainly through the work of Li Xingmin's academic research in the political and ideological changing environment since 1978，six aspects of the breakthrough in theoretical research were obtained，realizing the recognition of “physics crisis and revolution”.The work has the dual significance of academic research and ideological emancipation.