Abstract: Zhou Zuoren paid great attention to the enlightenment of thought and attempted the newborn of the literary to reconstruct the national spirit.When he participated in editing the literature publication, he initiated positively the multiple ways of the modern intellectual'speech in view of the Chinese national conditions.During the period of "YU Si Weekly", he initiated the editorial concept of enlightenment as the subject and the free competition in the literature.The editorial practice which included the column design and the attentions to the effect of readers had shown the ideological, knowledgeable and interesting character of the publication.At the same time, by the comparison of "Modern Review Weekly", "YU Si Weekly" had emphasized the investment of the writer main body spirits and the construction of main body personality charm.The translation practices and the theory discussions complemented each other, which further showed the unique importance of Zhou Zuoren's editorial style.